Particle detector application and principle

Application of particle detector

The particle detector is used in drug detection and uses light barrier technology to inspect insoluble particles in intravenous drip infusion (100 mL or more). Each 1 mL contains no more than 25 particles >10 μm, including 25 μm or more No more than 3 particles. In the 2010 edition of the Chinese Pharmacopoeia, the second part of the “Insoluble Particle Inspection Law” specifies the size and number of insoluble particles in intravenous injections and sterile bulk drugs for intravenous injection using instruments based on the principle of photodisordering.

The principle of particle detector

The principle of the sensor in the optical barrier method: the liquid to be detected passes through a specially designed flow cell, and the incident light beam perpendicular to the liquid flow is weakened by being blocked by the particles in the liquid, so that the signal output by the sensor changes, and this signal changes with The size of the cross-sectional area when particles pass through the beam is proportional. This proportional relationship can reflect the size of the particles. Each particle causes a voltage pulse signal as it passes through the beam. The number of pulses reflects the number of particles. Particle detectors mainly include: samplers, sensors, and computer-controlled detection and data processing systems. The measurement particle size range is: 2~100um; detection particle size concentration is 0~10000/ml. The domestic particle detector used for drug detection and having the light barrier principle was independently developed by Tianda Tianfa Technology Co., Ltd. in the mid-1990s.